Recombinant human TNFRSF1A protein with C-terminal human Fc tag
Product Sizes
50 µg
£646.00
32-17378-50UG
About this Product
- SKU:
- 32-17378
- Additional Names:
- CD120a; FPF; p55; p55-R; p60; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR55; TNFR60
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 45.54 kDa after removal of the signal peptide. The apparent molecular mass of TNFRSF1A-hFc is approximately 55-70 kDa due to glycosylation This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms; respectively; of its ligand; tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation; which plays a role in cell survival; apoptosis; and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor; which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS); characterized by fever; abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:32-17378.jpg
