Recombinant human CCR1 protein with C-terminal human Fc tag
Product Sizes
50 µg
£646.00
32-17277-50UG
About this Product
- SKU:
- 32-17277
- Additional Names:
- CD191; CKR-1; CKR1; CMKBR1; HM145; MIP1aR; SCYAR1
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 39.27 kDa after removal of the signal peptide. This gene encodes a member of the beta chemokine receptor family; which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha); regulated on activation normal T expressed and secreted protein (RANTES); monocyte chemoattractant protein 3 (MCP-3); and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response; and susceptibility to virus and parasite. This gene and other chemokine receptor genes; including CCR2; CCRL2; CCR3; CCR5 and CCXCR1; are found to form a gene cluster on chromosome 3p.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
