Recombinant human CALR protein with C-terminal human Fc tag
Product Sizes
50 µg
£805.00
32-17272-50UG
About this Product
- SKU:
- 32-17272
- Additional Names:
- cC1qR; CRT; HEL-S-99n; RO; SSA
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 79.53 kDa after removal of the signal peptide. Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum; and is involved in a variety of cellular processes; among them; cell adhesion. Additionally; it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus; suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms; including the myeloproliferative type.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
