RELM b Recombinant Protein
Product Sizes
25 µg
£528.00
32-1725-25UG
About this Product
- SKU:
- 32-1725
- Additional Names:
- Resistin-like beta||RELM beta||Cysteine-rich secreted protein FIZZ2||Colon and small intestine-specific cysteine-rich protein||Cysteine-rich secreted protein A12-alpha-like 1||Colon carcinoma-related gene protein||RELM-b||XCP2||HXCP2.
- Extra Details:
- Source : Escherichia Coli. RELM-b Human Recombinant produced in E.Coli is a disulfide-linked homodimer; non-glycosylated; polypeptide chain containing 2 x 89 amino acids and having a total molecular mass of 19kDa. RELM-b is purified by proprietary chromatographic techniques. RELM-beta (Resistin-Like Molecule-beta) is a member of a recently identified family of secreted proteins containing a conserved cystein-rich C-terminus. The RELM family consists of resistin (also called FIZZ3); RELM-alfa (FIZZ1); RELM-beta (FIZZ2) and RELM-gamma. Only resisistin and RELM-beta were found in humans whereas all four RELM family members were identified in rodents.RELM-beta appears to be produced as a homodimer exclusively by intestinal goblet cells and can be found in high quantities in stool. Remarkably; stool of germ-free mice displaying sterile intestinal tract does not contain RELM-beta until bacterial colonization takes place after pathogen-free mice entered natural environment. Some; but not all; colon carcinoma cell lines secrete RELM-beta into the cell culture supernatant.The physiological function of RELM-beta is not known. High doses of recombinant RELM-beta showed hyperglycemic effects including lowered glucose disposal and increased hepatic glucose production in mice.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized RELM-b although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution RELM-b Human Recombinant should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
