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Recombinant human IL15RA protein with C-terminal human Fc tag

Product Sizes
50 µg
£585.00
32-17242-50UG
About this Product
SKU:
32-17242
Additional Names:
CD215
Extra Details:
Expression Host : HEK293 The protein has a predicted molecular mass of 54.78 kDa after removal of the signal peptide. This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits; IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha; an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA; IL15RA is capable of binding IL15 with high affinity independent of other subunits; which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules