Recombinant human IL10R protein with C-terminal human Fc tag
Product Sizes
50 µg
£750.00
32-17239-50UG
About this Product
- SKU:
- 32-17239
- Additional Names:
- CD210;CD210a;CDW210A;HIL-10R;IL-10R1;IL10R
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 49.06 kDa after removal of the signal peptide. The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10; and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants; one protein-coding and the other not protein-coding; have been found for this gene.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
