Recombinant human NECTIN4 protein with C-terminal human Fc tag
Product Sizes
50 µg
£646.00
32-17234-50UG
About this Product
- SKU:
- 32-17234
- Additional Names:
- EDSS1; LNIR; nectin-4; PRR4; PVRL4
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 60.5 kDa after removal of the signal peptide. This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1; an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
