Recombinant human IL13 protein with C-terminal human Fc tag
Product Sizes
50 µg
£823.00
32-17232-50UG
About this Product
- SKU:
- 32-17232
- Additional Names:
- IL-13; P600
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 37.84 kDa after removal of the signal peptide. This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression; and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity; thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene; IL3; IL5; IL4; and CSF2 form a cytokine gene cluster on chromosome 5q; with this gene particularly close to IL4.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
