Recombinant human CRLF2 protein with C-terminal human Fc tag
Product Sizes
50 µg
£649.00
32-17224-50UG
About this Product
- SKU:
- 32-17224
- Additional Names:
- CRL2; CRLF2Y; TSLPR
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 48.51 kDa after removal of the signal peptide. This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R); the encoded protein and TSLP activate STAT3; STAT5; and JAK2 pathways; which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14; or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
