Recombinant human CD4 protein with C-terminal human Fc tag
Product Sizes
50 µg
£649.00
32-17220-50UG
About this Product
- SKU:
- 32-17220
- Additional Names:
- CD4;CD4mut;LEU3
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 65.67 kDa after removal of the signal peptide. This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes; but also in B cells; macrophages; granulocytes; as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation; and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
