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Recombinant human TNFRSF11A protein with C-terminal human Fc tag

Product Sizes
50 µg
£646.00
32-17213-50UG
About this Product
SKU:
32-17213
Additional Names:
CD265; FEO; LOH18CR1; ODFR; OFE; OPTB7; OSTS; PDB2; RANK; TRANCER
Extra Details:
Expression Host : HEK293 The protein has a predicted molecular mass of 45.65 kDa after removal of the signal peptide. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins; through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis; autosomal recessive osteopetrosis; and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules