Recombinant human CXC-R3 protein with C-terminal human Fc tag
Product Sizes
50 µg
£656.00
32-17193-50UG
About this Product
- SKU:
- 32-17193
- Additional Names:
- C-X-C chemokine receptor type 3;CXC-R3;CXCR-3;CKR-L2?G protein-coupled receptor 9?CD183?IP-10 receptor
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 31.35 kDa after removal of the signal peptide. This gene encodes a G protein-coupled receptor with selectivity for three chemokines; termed CXCL9/Mig (monokine induced by interferon-g); CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic; most notably integrin activation; cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine; CXCL4/PF4 (PMID:12782716).
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
