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Recombinant human ITGAM protein with C-terminal human Fc tag

Product Sizes
50 µg
£649.00
32-17168-50UG
About this Product
SKU:
32-17168
Additional Names:
CD11B; CR3A; MAC-1; MAC1A; MO1A; SLEB6
Extra Details:
Expression Host : HEK293 The protein has a predicted molecular mass of 145.2 kDa after removal of the signal peptide. This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'); or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium; and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules