Recombinant human CSF1R protein with C-terminal6Ã-His tag
Product Sizes
50 µg
£680.00
32-17052-50UG
About this Product
- SKU:
- 32-17052
- Additional Names:
- CSF1R;C-FMS;CD115;CSFR;FIM2;FMS;M-CSFR
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 55.6 kDa after removal of the signal peptide. The protein encoded by this gene is the receptor for colony stimulating factor 1; a cytokine which controls the production; differentiation; and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL); HL cell lines and anaplastic large cell lymphoma.
- Immunogen:
- CSF1R (IIe20-Leu514) ; 6 His tag C-term
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
