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Recombinant human B7-2 protein with C-terminal mouse Fc and6Ã-His tag

Product Sizes
50 µg
£649.00
32-17034-50UG
About this Product
SKU:
32-17034
Additional Names:
CD86; B7-2; B70; CD28LG2; LAB72; MGC34413
Extra Details:
Expression Host : HEK293 The protein has a predicted molecular mass of 52.4 kDa after removal of the signal peptide. This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells; and it is the ligand for two proteins at the cell surface of T cells; CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg