Recombinant human GITR protein with C-terminal human Fc and6Ã-His tag
Product Sizes
50 µg
£734.00
32-17018-50UG
About this Product
- SKU:
- 32-17018
- Additional Names:
- AITR; GITR; TNFRSF18; CD357
- Extra Details:
- Expression Host : HEK293 The protein has a predicted molecular mass of 51-52 kDa after removal of the signal peptide. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Purification:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
