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Recombinant human B7-H3 protein with C-terminal mouse Fc and6Ã-His tag

Product Sizes
50 µg
£688.00
32-17012-50UG
About this Product
SKU:
32-17012
Additional Names:
B7-H3; CD276; B7 homolog 3
Extra Details:
Expression Host : HEK293 The protein has a predicted molecular mass of 70-75 kDa after removal of the signal peptide. The protein encoded by this gene belongs to the immunoglobulin superfamily; and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors; the protein is preferentially expressed only in tumor tissues. Additionally; it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA; and there is an inverse correlation between the expression of this protein and miR29 levels; suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg
Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human B7-H3; mFc-His tagged protein can bind Anti-B7-H3 Neutralizing antibody in a linear range of 0.24-31.25 ng/ml.
Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human B7-H3; mFc-His tagged protein can bind Anti-B7-H3 Neutralizing antibody in a linear range of 0.24-31.25 ng/ml.