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Recombinant human 4-1BB protein with C-terminal mouse Fc and6Ã-His tag

Product Sizes
50 µg
£734.00
32-17011-50UG
About this Product
SKU:
32-17011
Additional Names:
TNFRSF9; 4-1BB; CD137; CDw137; ILA
Extra Details:
Expression Host : HEK293 The protein has a predicted molecular mass of 54-60 kDa after removal of the signal peptide. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion; survival; and development of T cells. It can also induce proliferation in peripheral monocytes; enhance T cell apoptosis induced by TCR/CD3 triggered activation; and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Purification:
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -80[o]C for 12 months (Avoid repeated freezing and thawing)
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg
Figure 2. HEK293 cell line transfected with irrelevant protein (B) and human 4-1BB Ligand (A) were surface stained with Human 4-1BB; mFc-His tagged protein 1µg/ml followed by Alexa 488-conjugated anti-mouse IgG secondary antibody.
Figure 2. HEK293 cell line transfected with irrelevant protein (B) and human 4-1BB Ligand (A) were surface stained with Human 4-1BB; mFc-His tagged protein 1µg/ml followed by Alexa 488-conjugated anti-mouse IgG secondary antibody.