oPrl A Mutant Recombinant Protein
Product Sizes
50 µg
£528.00
32-1693-50UG
About this Product
- SKU:
- 32-1693
- Additional Names:
- Mammotropin||Luteotropic hormone||Luteotropin||PRL||Prolactin.
- Extra Details:
- Source : Escherichia Coli. Prolactin Ovine Antagonist Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 199 amino acids and an additional Ala at N-terminus and having a molecular mass of 23kDa. The mutant R129G is DES 9 amino acids truncated form from its N-terminus which has higher inhibitory activity. Ovine Prolactin Antagonist is purified by proprietary chromatographic techniques. Prolactin is a lactogenic hormone secreted by the adenohypophysis .Besides its major action on lactation; in some species prolactin exerts effects on reproduction; maternal behavior; fat metabolism; immunomodulation and osmoregulation.Prolactin has been shown also to have cytokine-like activities and to have important immunoregulatory activities. It contributes to the development of lymphoid tissues and the maintenance of physiological immune function and also modulates a variety of T-cell immune responses. Prolactin has been reported to activate cellular proliferation in nonreproductive tissue; such as liver; spleen; and thymus. It induces significant proliferation in aortic smooth muscle cells and also enhances proliferation of these cells induced by PDGF . Prolactin also appears to be directly mitogenic for pancreatic beta cells. Prolactin is also mitogenic for cultured astrocytes.
- Purification:
- Greater than 99.0% as determined by Gel Filtration & SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized Ovine Prolactin Antagonist although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Ovine Prolactin Antagonist should be stored at 4[o]C between 2-7 days and for future use below -18?C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
