rPDGF BB Recombinant Protein
Product Sizes
10 µg
£528.00
32-1663-10UG
About this Product
- SKU:
- 32-1663
- Additional Names:
- Platelet-derived growth factor subunit B||PDGF subunit B||PDGF-2||Platelet-derived growth factor B chain||Platelet-derived growth factor beta polypeptide||Pdgfb||SIS||c-sis.
- Extra Details:
- Source : Escherichia Coli. PDGF-BB Rat Recombinant produced in E.coli is a disulfide-linked homodimeric; non-glycosylated; polypeptide of two B chains containing 2x109 amino acids (218 amino acids in total) and having a molecular mass of 24.4 kDa.The PDGF-BB is purified by proprietary chromatographic techniques. PDGF-BB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB); where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7; at sites where this gene and that for COL1A1 are located; are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two splice variants have been identified for this gene.
- Purification:
- Greater than 98.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized Platelet-derived Growth Factor BB although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution PDGF BB should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
