OPG His Recombinant Protein
Product Sizes
50 µg
£528.00
32-1641-50UG
About this Product
- SKU:
- 32-1641
- Additional Names:
- TNFRSF11B||OPG||OCIF||Osteoclastogenesis inhibitory factor||TR1||MGC29565.
- Extra Details:
- Source : Escherichia Coli. Recombinant Human OCIF produced in E.coli cells is a single; non-glycosylated; polypeptide chain containing amino acids 201-401 and having a molecular mass of 31 kDa which includes a 4 kDa His tag.The OPG is purified by proprietary chromatographic techniques. Osteoprotegerin; which is a member of the tumor necrosis factor receptor superfamily and is involved in the regulation of bone metabolism. OPGand its ligand (OPGL) are cytokines regulating osteoclasto-genesis. OPGL binds to receptors on the surface of preosteoclasts and stimulates their differentiation into active osteoclasts. This leads to osteoresorption. OPG inhibits this osteoclasto-genesis (OPG is secreted by osteoblasts; and binds to OPGL; thus inhibiting maturation of osteoclasts and osteoresorption). The degree and activity of osteoresorption depend mainly on the balance between OPG and its ligand (OPGL); factors increasing OPGL expression mostly reduce OPG expression and vice versa.
- Purification:
- Greater than 80.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized Osteoprotegerin although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution OCIF should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
