MIA His Recombinant Protein
Product Sizes
20 µg
£528.00
32-1604-20UG
About this Product
- SKU:
- 32-1604
- Additional Names:
- Melanoma-derived growth regulatory protein precursor||Cartilage-derived retinoic acid-sensitive protein||CD-RAP||MIA.
- Extra Details:
- Source : Escherichia Coli. MIA Human Recombinant produced in E.coli is a single; non-glycosylated polypeptide chain containing 128 amino acids (25-131) and having a molecular mass of 14.4 kDa.MIA is fused to a 23 amino acid His-tag at N-terminus. The Melanoma Inhibitory protein (MIA) was identified as an inhibitor of in vitro growth of malignant melanoma cells. The protein contains a SH3 domain. MIA acts as a potent tumor cell growth inhibitor for malignant melanoma cells and some other neuroectodermal tumors; including gliomas; in an autocrine fashion. In a study of human melanoma cell lines with different metastatic capacity MIA mRNA expression appeared to be inversely correlated with pigmentation. MIA has been shown to represent a very sensitive and specific serum marker for systemic malignant melanoma that might be useful for staging of primary melanomas; detection of progression from localized to metastatic disease during follow-up; and monitoring therapy of advanced melanomas.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
