IL35 Recombinant Protein
Product Sizes
10 µg
£528.00
32-1521-10UG
About this Product
- SKU:
- 32-1521
- Extra Details:
- Source : HEK 293 cells. IL35 Human Recombinant produced in HEK 293 cells is comprised of a p35 subunit from IL-12 (Accession # p29459) and a EBI3 (Accession # q14213) subunit from IL-27. IL35 is a heterodimeric polypeptide chain containing 442 amino acids; with a predicted molecular weight of 49 kDa. From N terminus to C terminus; the molecule is comprised of a poly His tag; the EBI3 subunit; a G rich linker and the p35 subunit. Interleukin-35 is a glycosylated; disulfide-linked; heterodimeric protein comprised of the p35 subunit of IL-12 (IL-12 alpha) and the beta subunit of IL-27 (EBI3). IL35 is expressed by regulatory T-cells (Tregs); macrophages and some trophoblast and dendritic cells. IL-35 is produced in response to inflammation and generally serves as an inflammation suppressor. Interleukin-35 curbs inflammation by applying multiple activities; including the stimulation of regulatory T-cells and the inhibition of Th17 cells.
- Purification:
- Greater than 95.0% as determined by analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized IL35 although stable at room temperature for 3 weeks; should be stored desiccated below -180C. Upon reconstitution IL35 should be stored at 40C between 2-7 days and for future use below -180C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
