IL 33 His Recombinant Protein
Product Sizes
10 µg
£528.00
32-1516-10UG
About this Product
- SKU:
- 32-1516
- Additional Names:
- Interleukin 33||DVS27||NF-HEV||NKHEV||C9orf26||Interleukin-1 family member 11||IL- 1F11||Nuclear factor from high endothelial venules||NFEHEV||DKFZp586H0523||RP11-575C20.2||IL-33||IL33.
- Extra Details:
- Source : Escherichia Coli. Interleukin-33 Human Recombinant produced in E.Coli is a single; non-glycosylated; Polypeptide chain containing 159 amino acids C-terminal fragment (112-270) having a molecular weight of 22.49kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The IL-33 His is purified by proprietary chromatographic techniques. Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1; which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1); which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo; IL-33 induces expression of IL-4; IL-5; IL-13 and leads to severe pathological changes in mucosal organs and in vitro; it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. Please avoid freeze thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
