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IL 23 His Recombinant Protein

Product Sizes
10 µg
£528.00
32-1499-10UG
About this Product
SKU:
32-1499
Additional Names:
Interleukin 23 alpha subunit p19||Interleukin-12 subunit beta p40||SGRF||IL23P19||IL-23-A||interleukin-six||G-CSF related factor||JKA3 induced upon T-cell activation||interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic lymphocyte matu
Extra Details:
Source : HEK 293 cells. IL-23 Human Recombinant produced in HEK 293 cells is a heterodimer (IL23A co-transfected with IL12B); containing one polypeptide chain of IL23 protein (19.77kDa) fused with a C-terminal His tag and one polypeptide chain of IL12b-Flag (35.69kDa).The IL-23 is purified by proprietary chromatographic techniques. IL23 is composed of a subunit of the heterodimeric cytokine IL23 and the p40 subunit of interleukin 12 (IL12B). Interleukin-23 (IL-23) belongs to the IL-12 family and is produced by antigen presenting cells. IL-23 using IL12RB1 and IL-23R (specific for IL-23) can activate STAT and NF-kB pathways and stimulate the production of interferon-gamma. ). IL-23 is known to take a vital part in the inflammation process and is associated with auto immune diseases. However; unlike IL12; which acts primarily on naive CD4(+) T cells; IL23 preferentially acts on memory CD4(+) T cells.
Purification:
Greater than 90.0% as determined by analysis by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.Please avoid freeze thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules
  • Manufacturer's Data Sheet:1.jpg