mIL 22 Recombinant Protein
Product Sizes
10 µg
£528.00
32-1494-10UG
About this Product
- SKU:
- 32-1494
- Additional Names:
- IL-TIF||TIFa||IL-10-related T-cell-derived-inducible factor||IL-22||ILTIF||IL-D110||zcyto18||MGC79382||MGC79384||TIFIL-23.
- Extra Details:
- Source : Escherichia Coli. Interleukin-22 Mouse Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 147 amino acids and having a molecular mass of 16.7 kDa. The Murine IL-22 is purified by proprietary chromatographic techniques. Interleukin-22 (IL-22); also known as IL-10-related T cell-derived inducible factor (IL-TIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acids signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with human IL-22 and IL-10; respectively. IL-22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection; suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits; IL-22R (previously an orphan receptor named CRF2-9) and IL-10R (previously known as CRF2-4); belonging to the class II cytokine receptor family.
- Purification:
- Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized Interleukin-22 although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution IL22 should be stored at 4[o]C between 2-7 days and for future use below -18[o]C.Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:1.jpg
