HIV-1 gp41 Subtype-c
Product Sizes
100 µg
£583.00
32-13839-100UG
0.5 mg
£1160.00
32-13839-0.5MG
About this Product
- SKU:
- 32-13839
- Extra Details:
- Source:Escherichia Coli. Physical Appearance:Sterile Filtered clear solution. Biological Activitynull Human immunodeficiency virus (HIV) is a retrovirusthat can lead to a condition in which the immune systembegins to fail; leading to opportunistic infections. HIV primarily infects vital cells in the humanimmune systemsuch as helper T cells(specifically CD4+ T cells); macrophagesand dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly; direct viral killing of infected cells; secondly; increased rates of apoptosisin infected cells; and thirdly; killing of infected CD4+ T cells by CD8 cytotoxic lymphocytesthat recognize infected cells. When CD4+ T cell numbers decline below a critical level; cell-mediated immunityis lost; and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus; part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses; which are characteristically responsible for long-duration illnesses with a long incubation period.HIV-1 gp41 Subtype-c reacts to the specific antibody from HIV1 infection; in lateral flow assay; it is usually coated on the membrane to capture the specific antibody from HIV1 infection. Recombinant HIV-1 gp41 Subtype-c produced in E. coli having a Mw of 36kDa.Recombinant HIV-1 gp41 Subtype-c is fused to GST tag at its N-terminus and purified by proprietary chromatographic technique.
- Purification:
- Protein is >90% pure as determined by 10% PAGE (coomassie staining).
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
