SOST Mouse
Product Sizes
2 µg
£452.00
32-13801-2UG
10 µg
£528.00
32-13801-10UG
About this Product
- SKU:
- 32-13801
- Additional Names:
- SOST; Sclerostin; 5430411E23Rik.
- Extra Details:
- Source:HEK293 cells.Physical Appearance:Sterile Filtered colorless solution.Biological ActivitynullSclerostin (SOST) is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein antagonists. Sclerostin functions as a negative regulator of bone growth; by inhibiting bone formation. SOST is expressed mainly in the bone; cartilage; kidney; liver; bone marrow and primary osteoblasts differentiated for 21 days. SOST gene defects cause sclerosteosis and bone dysplasia.SOST Mouse Recombinant produced in HEK293 cells is a single; glycosylated polypeptide chain (24-211 a.a) containing 194 amino acids and having a molecular mass of 21.9 kDa.SOST is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
- Format:
- SOST protein (0.25mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
