PDCD1 Human; Active
Product Sizes
5 µg
£452.00
32-13787-5UG
20 µg
£528.00
32-13787-20UG
About this Product
- SKU:
- 32-13787
- Additional Names:
- Programmed cell death protein 1; CD279; hPD-1; SLEB2; hPD-l; hSLE1; PD-1; PD1; PDCD1.
- Extra Details:
- Source:HEK293 Cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivityMeasured by its binding ability in a functional ELISA with Human PD-L1/B7-H1PDCD1 is a cell surface membrane protein of the immunoglobulin superfamily. PDCD1 is expressed in pro-B-cells and is thought to have a role in their differentiation. In mice; expression of PDCD1 gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for the PDCD1 gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that the PDCD1 gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.PDCD1 Human Recombinant produced in HEK293 Cells is a single; glycosylated polypeptide chain containing 383 amino acids (21-170 a.a) and having a molecular mass of 42.9kDa.PDCD1 is fused to a 233 amino acid hIgG-His-Tag at C-terminus & purified by proprietary chromatographic techniques.
- Format:
- The PDCD1 solution (0.5mg/1ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.
- Purification:
- Greater than 95.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
