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LILRB2 Human

Product Sizes
2 µg
£452.00
32-13779-2UG
10 µg
£528.00
32-13779-10UG
About this Product
SKU:
32-13779
Additional Names:
Leukocyte Immunoglobulin-like Receptor; CD85D; CD85d; CD85 antigen-like family member D; CD85d antigen; ILT-4; ILT4; ILT4CD85d; Ig-like transcript 4; Immunoglobulin-like transcript 4; LILRB2; LIR2; LIR-2; LIR2CD85D; Leukocyte immunoglobulin-like receptor 2; MIR10; MIR-10; MIR10LILRA6; Monocyte/macro
Extra Details:
Source:HEK293 Cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivitynullLeukocyte Immunoglobulin Like Receptor B2 (LILRB2) is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LILRB2is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response.LILRB2controls inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.LILRB2competes with CD8 alpha for MHC I binding. LILRB2binds to classical MHC I proteins as well as the non-classical HLA-G1 and HLA-F molecules.LILRB2 Human Recombinant produced in HEK293 Cells is a single; glycosylated polypeptide chain containing 444 amino acids (24-461 a.a) and having a molecular mass of 48.3kDa.LILRB2 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Format:
The LILRB2 solution (0. 5mg/ml) contains phosphate buffered saline (pH7.4) and 20% glycerol.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules