CFD Human
Product Sizes
1 µg
£475.00
32-13751-1UG
5 µg
£600.00
32-13751-5UG
About this Product
- SKU:
- 32-13751
- Additional Names:
- Complement factor D; Adipsin; C3 convertase activator; Properdin factor D; CFD; DF; PFD.
- Extra Details:
- Source:Human Plasma.Physical Appearance:Sterile filtered solution.Biological ActivitynullCFD is an important component of the alternative pathway of complement activation. CFD cleaves and activates factor B when it binds C3b or a C3b-like protein such as C3 or CVF. CFD is a serine protease that exists as a mature protease; but it exhibits a highly restricted specificity and it appears to be substrate activated. CFD cleaves factor B bound to C3b leading to the release of the Ba fragment and leaving the Bb fragment bound to C3b. The C3b;Bb complex is called a C3 or C5 convertase because it converts these proteins to their active forms by cleaving off the small peptides C3a and C5a; respectively.Human Complement Factor D produced in Human plasma is glycosylated polypeptide chain having a total molecular mass of 24kDa.
- Format:
- CFD protein solution contains 10mM Sodium phosphate and 145mM NaCl; pH 7.3.
- Purification:
- Greater than 95.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- CFD Human is stable at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen below -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
