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Proteins and Peptides

CFB Human; Native

Product Sizes
20 µg
£600.00
32-13748-20UG
100 µg
£1030.00
32-13748-100UG
About this Product
SKU:
32-13748
Additional Names:
CFB; C3/C5 convertase; Glycine-rich beta glycoprotein; GBG; PBF2; Properdin factor B; BF; BFD; AHUS4; ARMD14; CFAB; CFBD; FB; FBI12; GBG; H2-Bf.
Extra Details:
Source:Human Plasma.Physical Appearance:Sterile filtered solution.Biological ActivitynullComplement Factor B; also known as CFB; encodes complement factor B which is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Once the alternative pathway is activated it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which connects with C3b to form the alternative pathway C3 convertase. Also; Bb is involved in the proliferation of preactivated B lymphocytes; while Ba inhibits their proliferation.Human Complement Factor B produced in Human plasma is glycosylated polypeptide chain having a total molecular mass of 93kDa.
Format:
CFB protein solution contains 10mM Sodium phosphate and 145mM NaCl; pH 7.2.
Purification:
Greater than 95.0% as determined by SDS-PAGE.
Shipping Conditions:
Blue Ice
Storage Conditions:
CFB Human is stable at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen below -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Supplier:
Abeomics
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules:Native