CD27 Human; HEK
Product Sizes
2 µg
£452.00
32-13743-2UG
10 µg
£528.00
32-13743-10UG
About this Product
- SKU:
- 32-13743
- Additional Names:
- Tumor Necrosis Factor Receptor Superfamily Member 7; T-Cell Activation Antigen CD27; CD27 Molecule; CD27 Antigen; T Cell Activation Antigen S152; CD27L Receptor; TNFRSF7; S152; Tp55; T14.
- Extra Details:
- Source:HEK293 Cells. Physical Appearance:Sterile Filtered colorless solution. ED50 range is = 0.8 ug/ml. Defined by its binding ability in a functional ELISA with Human CD27 Ligand/TNFSF7. CD27 belongs to the TNF-receptor superfamily. CD27 is necessary for initiation and long-term maintenance of T cell immunity. CD27 binds to ligand CD70; and has a crucial role in regulating B-cell activation and immunoglobulin synthesis. The CD27 receptor transduces signals which result in the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 mediate the signaling process of CD27. CD27-binding protein (SIVA); which is a proapoptotic protein; can bind to the CD27 receptor and is believed to have a significant role in the apoptosis induced by CD27. CD27 Human Recombinant produced in HEK cells is a single; glycosylated; polypeptide chain (20-191 a.a) containing a total of 411 amino acids; having a molecular mass of 46.2kDa. CD27 is fused to a 239 amino acid hIgG-His-Tag at C-terminus;and is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 95.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
