C6 Human
Product Sizes
20 µg
£600.00
32-13735-20UG
100 µg
£1030.00
32-13735-100UG
About this Product
- SKU:
- 32-13735
- Additional Names:
- Complement component C6; C6.
- Extra Details:
- Source:Human Plasma.Physical Appearance:Sterile filtered solution.Biological ActivitynullC6 is necessary for membrane attack complex formation and is activated by binding to recently-formed C5b at the cell membrane.Each pathway of complement activation generates proteolytic enzyme complexes which are bound to the target surface. These enzymes cleave a peptide bond in the larger alpha chain of C5 releasing C5a and activating C5b. Although C5b is unstable it remains bound to the activating complex for a few minutes during which it binds a single C6 from the surrounding fluid or it decays and is no longer capable of forming MAC. The C5b;6 complex may also remain connected to the C3/C5 convertase where the binding of a single C7 exposes a membrane-binding region and C5b;6;7 can enter into the bilipid layer of the target cell.Human Complement C6 produced in Human plasma having a molecular mass of 105 kDa.
- Format:
- C6 protein solution contains phosphate buffer saline; pH 7.2.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- C6 Human is stable at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen below -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
