ErbB4 Human
Product Sizes
2 µg
£452.00
32-13707-2UG
10 µg
£528.00
32-13707-10UG
About this Product
- SKU:
- 32-13707
- Additional Names:
- Receptor tyrosine-protein kinase erbB-4; Proto-oncogene-like protein c-ErbB-4; Tyrosine kinase-type cell surface receptor HER4; p180erbB4; 4ICD; E4ICD; s80HER4; ERBB4; HER4; receptor tyrosine-protein kinase erbB-4 isoform JM-a/CVT-1; receptor tyrosine-protein kinase erbB-4; tyrosine kinase-type cell
- Extra Details:
- Source:HEK293 Cells. Physical Appearance:Sterile filtered colorless solution. Biological ActivityMeasured by its binding ability in a functional ELISA with Human NRG1. The ED50 range = 0.2 ug/ml. Tyrosine Kinase ErbB-4 (ErbB4) is a receptor tyrosine kinase that is a member of the epidermal growth factor receptor family whose members play a role as receptors for the EGF family of growth factors. ErbB4is a single-pass type I transmembrane protein with multiple furin-like cysteine rich domains;PDZ domain binding motif; a tyrosine kinase domain and a phosphotidylinositol-3 kinase binding site. ErbB4binds its ligands with low affinity and is expressed in normal skeletal muscle; heart; pituitary; brain and some breast carcinomas. Monomeric ErbB4 takes part in neuronal development and development of the heart and cancer. ErbB4 Human Recombinant produced in HEK293 Cells is a single; glycosylated polypeptide chain containing 863 amino acids (26-649 a.a) and having a molecular mass of 96.6 kDa.ErbB4 is fused to a 239 amino acid hIgG-His-Tag at C-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
