IL17A Canine
Product Sizes
2 µg
£452.00
32-13654-2UG
10 µg
£528.00
32-13654-10UG
About this Product
- SKU:
- 32-13654
- Additional Names:
- IL17A; IL17; IL-17A; CTLA8; CTLA8; Interleukin 17A; Interleukin-17A; cytotoxic T-lymphocyte-associated serine esterase 8.
- Extra Details:
- Source:HEK293 cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivityThe activity is determined by the IL-6 ELISA in a using NIH/3T3 mouse embryonic fibroblast cells. The ED50 range = 10 ng/ml.IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2); as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis; psoriasis and multiple sclerosis.IL17A Canine Recombinant produced in HEK293 cells is a single; glycosylated polypeptide chain (29-155a.a) containing 133 amino acids and having a molecular mass of 15.6kDa.IL17A is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Format:
- IL17A protein (0.5mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
