IL5 Canine
Product Sizes
2 µg
£452.00
32-13653-2UG
10 µg
£528.00
32-13653-10UG
About this Product
- SKU:
- 32-13653
- Additional Names:
- Interleukin-5; IL-5; EDF; TRF; Eosinophil differentiation factor; T-cell replacing factor.
- Extra Details:
- Source:Sf9; Baculovirus cells.Physical Appearance:Sterile Filtered colorless solution.Biological ActivityMeasured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range = 15 ng/ml.The protein encoded by IL5is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL5is a main regulator of eosinopoiesis; eosinophil maturation and activation. The elevated production of IL5is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer; whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). Interleukin-5; together with those for interleukin 4 (IL4); interleukin 13 (IL13); and CSF2; form a cytokine gene cluster on chromosome 5. Interleukin-5; IL4; and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.IL5 Canine produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 119 amino acids (22-134 aa) and having a molecular mass of 13.9kDa.IL5 is fused to a 6 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.
- Format:
- The IL5 solution (0.25mg/ml) contains 10% Glycerol and Phosphate-Buffered Saline (pH 7.4).
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
