EREG Human; HEK
Product Sizes
2 µg
£452.00
32-13644-2UG
10 µg
£528.00
32-13644-10UG
About this Product
- SKU:
- 32-13644
- Additional Names:
- EPR; Epiregulin; Ep; ER; Proepiregulin; EREG.
- Extra Details:
- Source:HEK293 cells.Physical Appearance:Sterile filtered colorless solution.Biological ActivityMeasured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblast cells. The ED50 range = 1ug/ml.Epiregulin is part of the EGF family. Epiregulin functions as a ligand of EGFR; as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors.Epiregulin is expressed mostly in the placenta and peripheral blood leukocytes and in specific carcinomas of the bladder; lung; kidney and colon. Epiregulin stimulates the proliferation of keratinocytes; hepatocytes; fibroblasts and vascular smooth muscle cells. Epiregulin inhibits the growth of several tumor-derived epithelial cell lines. Human Epiregulin is initially synthesized as a glycosylated 19.0 kDa transmembrane precursor protein; which is processed by proteolytic cleavage to produce a 6.0 kDa mature secreted sequence.EREG Human Recombinant produced in HEK293 cells is a single; glycosylated polypeptide chain (63-108a.a) containing 289 amino acids and having a molecular mass of 32.6 kDa.EREG is fused to a 239 amino acid hIgG-His-Tag at C-terminus & purified by proprietary chromatographic techniques.
- Format:
- EREG protein (0.25mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH 7.4).
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules
- Manufacturer's Data Sheet:download_pdf.php
