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Antibodies

HBV Pre-S

Product Sizes
100 µg
£547.00
32-13593-100UG
0.5 mg
£1030.00
32-13593-0.5MG
About this Product
SKU:
32-13593
Additional Names:
Hepatitis B virus surface gene encodes 3 proteins: small (HBs); middle (MHBs) and large (LHBs) surface protein. These 3 proteins are translated from distinct start codons; however share a common reading frame and stop codon. HBs contains 226 amino acids; it is a major viral envelope component. MHBs
Extra Details:
Source: Escherichia Coli.Sterile Filtered solution.Hepatitis B virus surface gene encodes 3 proteins: small (HBs); middle (MHBs) and large (LHBs) surface protein. These 3 proteins are translated from distinct start codons; however share a common reading frame and stop codon. HBs contains 226 amino acids; it is a major viral envelope component. MHBs has extra 55 amino acids (Pre-S2) located to the N-terminus of HBs; LHBs has an additional 119 amino acids (Pre-S1). Pre-S is a region is comprised of Pre-S1 and S2; Pre-S1 has a vital role in receptor recognition; while Pre-S2 plays a part in translocation of virus into host cell. Clinically; HBV pre-S is linked with HBsAg and HBV DNA copies; which indicates active replication of virus; reduction of pre-S is typically associated with decreased HBV DNA copies; pointing to an improved predictor of treatment. In addition; Pre-S is a potential vaccine under development to enhance currently used HBsAg vaccine.Recombinant Hepatitis B Virus Pre-S produced in E.coli is a full length Pre-S of HBV subtype adw2; containing 174 amino acids; having a molecular weight of about 25kDa including a vector sequence and linked with a 6xHis tag at C- terminus.
Purification:
Protein is >95% pure as determined by 12% PAGE (coomassie staining).
Shipping Conditions:
Blue Ice
Storage Conditions:
HBV Pre-S although stable at 4[o]C for 1 week; should be stored below -18[o]C. Please prevent freeze thaw cycles.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody