HSPA5 Mouse
Product Sizes
1 µg
£452.00
32-13521-1UG
5 µg
£528.00
32-13521-5UG
About this Product
- SKU:
- 32-13521
- Additional Names:
- 78 kDa glucose-regulated protein; GRP-78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; Bip; Hspa5; Grp78; HSPA5; Hsce70.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered clear solution.Once Chinese hamster K12 cells are starved from glucose; the synthesis of GRP (glucose-regulated protein) expressed. HSPA5 also called BiP; is part of the HSP70 family and plays a role in the folding and assembly of proteins in the endoplasmic reticulum. HSPA5 plays a key role in monitoring protein transport through the cell. HSPA5 is a stress response protein which is induced by agents or conditions that adversely affect endoplasmic reticulum function. HSPA5 is crucial for the proper glycosylation; folding as well as for the maintenance of cell homeostasis and the prevention of apoptosis. HSPA5 is differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. HSPA5 guides posttranslational hepatitis B virus large envelope protein import into the mammalian ER. HSPA5 actively regulates multiple malignant phenotypes; including cell growth; migration; and invasion.HSPA5 Mouse Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 659 amino acids (20-655 a.a) and having a molecular mass of 72.9kDa. HSPA5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
