VNN1 Human
Product Sizes
2 µg
£452.00
32-13505-2UG
10 µg
£528.00
32-13505-10UG
About this Product
- SKU:
- 32-13505
- Additional Names:
- Vanin 1; Vascular Non-Inflammatory Molecule 1; Pantetheine Hydrolase; EC 3.5.1.92; Vanin-1; HDLCQ8; Tiff66; Pantetheinase; Vannin 1; EC 3.5.1; VNN1.
- Extra Details:
- Source: Escherichia Coli.Filtered White lyophilized (freeze-dried) powder.Vanin 1 (VNN1) belongs to the vanin family of proteins; which share extensive sequence similarity with each other; and also with biotinidase. This family includes secreted and membrane-associated proteins; a few of which have been described to participate in hematopoietic cell trafficking. No biotinidase activity has been established for any of the vanin proteins; nevertheless; they possess pantetheinase activity; which may have a role in oxidative-stress response. VNN1 protein; like its mouse homolog; is probably a GPI-anchored cell surface molecule. The mouse VNN1 protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. VNN1 is an amidohydrolase which hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5).VNN1 Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain (Gln22-Gly491) containing 480 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 53.5kDa.
- Purification:
- Greater than 95.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
