Recombinant Human TLR3 Human (C-Term His Tag)
Product Sizes
1 µg
£452.00
32-13478-1UG
5 µg
£528.00
32-13478-5UG
About this Product
- SKU:
- 32-13478
- Additional Names:
- Toll Like Receptor 3; Toll-Like Receptor 3; CD283 Antigen; CD283; IIAE2; Toll-like receptor 3.
- Extra Details:
- Source: Sf9; Baculovirus cells. Sterile Filtered colorless solution. TLR3 (Toll-like receptor 3) belongs to the toll-like receptor family which takes an essential part in pathogen recognition as well as activation of innate immunity. TLR3 has innate immune receptors for sensing microbial molecules in addition to damage-associated molecular patterns released from host cells. TLR3 recognizes dsRNA and activation of the receptor which induces the activation of NF-kappaB and the production of type I interferons. TLR3 signaling activation is related with ischemic preconditioning-induced protection against brain ischemia and attenuation of reactive astrogliosis. TLR3 is most plentifully expressed in the placenta & pancreas; and is limited to the dendritic subpopulation of the leukocytes. TLR3 produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 690 amino acids (23-704 a.a.) and having a molecular mass of 78.5kDa. (Molecular size on SDS-PAGE will appear at approximately 70-100kDa).TLR3 is expressed with an 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
- Manufacturer's Data Sheet:32-13478.jpg
