Streptolysin-O
Product Sizes
20 µg
£534.00
32-13461-20UG
100 µg
£727.00
32-13461-100UG
About this Product
- SKU:
- 32-13461
- Additional Names:
- Streptolysin O; Thiol-activated cytolysin; slo.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered white lyophilized powder.Streptolysin-O is a sulfhydryl-activated toxin which causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes; the Streptolysin-O protein undergoes a major conformation change; leading to its insertion in the host membrane and creation of an oligomeric pore complex. Cholesterol may be needed for binding to host membranes; membrane insertion and pore formation. Streptolysin-O can be reversibly inactivated by oxidation.Recombinant Streptococcus Pyogenes Streptolysin-O produced in E.coli is a single; non-glycosylated; polypeptide chain containing 538 amino acids and having a molecular mass of 60.1kDa.The Streptolysin-O is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 97.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized Streptolysin-O although stable at room temperature for 3 weeks; should be stored desiccated below -18[o]C. Upon reconstitution Streptolysin-O should be stored at 4[o]C between 2-7 days and for future use below -18[o]C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
