SIRPA Rat
Product Sizes
2 µg
£452.00
32-13426-2UG
10 µg
£528.00
32-13426-10UG
About this Product
- SKU:
- 32-13426
- Additional Names:
- Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; Macrophage membrane protein MFP150; Signal-regulatory pro
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered clear solution.Signal-Regulatory Protein Alpha; SIRPA belongs to the signal-regulatory-protein (SIRP) family; as well as theimmunoglobulin super family. The members of the SIRP family are receptor-type transmembrane glycoproteins which areinvolved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPA can bephosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2domain containing tyrosine phosphatases (PTP); and perform as substrates of PTPs. SIRPA take part insignal transduction mediated by a variety of growth factor receptors. CD47 has been shown to be a ligand forSIRPA.SIRPA Rat Recombinant produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 350 amino acids (32-373a.a) and having a molecular mass of 38.5kDa. (Migrates at 57-70kDa on SDS-PAGE under reducing conditions). SIRPA is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 95.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
