MTDH Human
Product Sizes
2 µg
£452.00
32-13326-2UG
10 µg
£528.00
32-13326-10UG
About this Product
- SKU:
- 32-13326
- Additional Names:
- Metadherin; Lysine-Rich CEACAM1 Co-Isolated Protein; Astrocyte Elevated Gene-1 Protein; Metastasis Adhesion Protein; Astrocyte Elevated Gene 1; 3D3/LYRIC; AEG-1; LYRIC; AEG1; LYRIC/3D3; 3D3; MTDH.
- Extra Details:
- Source: Escherichia Coli.Filtered White lyophilized (freeze-dried) powder.Metadherin (MTDH) downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. MTDH activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Furthermore; MTDH promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a central component in tumor cell expansion. In addition; MTDH promotes lung metastasis and also has an effect on bone and brain metastasis; possibly by enhancing the seeding of tumor cells to the target organ endothelium. Metadherin also induces chemoresistance.Metadherin Human Recombinant produced in E.Coli is a single; non-glycosylated; polypeptide chain (Val271-Asn456) containing 196 amino acids including a 10 aa His tag at N-terminus. The total calculated molecular mass is 21.5kDa.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store lyophilized protein at -20[o]C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4[o]C for a limited period of time; it does not show any change after two weeks at 4[o]C.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
