LRIG1 Mouse
Product Sizes
2 µg
£452.00
32-13299-2UG
10 µg
£528.00
32-13299-10UG
About this Product
- SKU:
- 32-13299
- Additional Names:
- Leucine-rich repeats and immunoglobulin-like domains protein 1; LIG-1; Lrig1; LIG1; D6Bwg0781e; Img
- Extra Details:
- Source: Sf9; Baculovirus cells.Sterile Filtered colorless solution.Leucine Rich Repeats And Immunoglobulin Like Domains 1 or LRIG1 is a protein; acting as is a pan-negative regulator of EGFR signal transduction. When studied along with ErbB proteins and Met kinase; LRIG1 was found to have regulation activities such as ubiquitination and lysosomal degradation increment of the receptors. Therefore; LRIG1 acts as a suppressor for tumors via cell proliferation control via negative regulation of tyrosine kinase receptors that belongs to the EGF protein family. LRIG1 expression is downregulated in cancer; and acts a prognostic tool for cancer development.LRIG1 Mouse produced in Sf9 Baculovirus cells is a single; glycosylated polypeptide chain containing 770 amino acids (35-796 a.a.) and having a molecular mass of 84.8kDa.LRIG1 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
