LMNA Human
Product Sizes
2 µg
£452.00
32-13294-2UG
10 µg
£528.00
32-13294-10UG
About this Product
- SKU:
- 32-13294
- Additional Names:
- Prelamin-A/C; Lamin-A/C; 70 kDa lamin; LMNA; LMN1; Renal carcinoma antigen NY-REN-32; Progerin.
- Extra Details:
- Source: Escherichia Coli.Sterile filtered colorless solution.Lamin-A is a major component of the nuclear lamina; a dynamic meshwork located just under the nuclear envelope and it is encoded by lamin A/C gene (LMNA). Lamin-A is synthesized as Prelamin A; a longer precursor that in vivo goes through a serial post-translational modifications that lead to mature Lamin A. Diverse mutations in the Lamin A/C gene are associated with different diseases that are collectively called laminophaties; including Emery-Dreifuss muscular dystrophy; familiar partial lipodystrophy; limb girdle muscular dystrophy; dilated cardiomyopathy; Charcot-Marie-Tooth disease; and Hutchinson-Gilford progeria syndrome.LMNA Human Recombinant fused with a His tag produced in E.Coli is a single; non-glycosylated; polypeptide chain containing 614 amino acids and having a molecular mass of 68.0kDa. The LMNA is purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks.Store; frozen at -20[o]C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
