HLA-G Human
Product Sizes
2 µg
£452.00
32-13260-2UG
10 µg
£528.00
32-13260-10UG
About this Product
- SKU:
- 32-13260
- Additional Names:
- Major Histocompatibility Complex; Class I; G; HLA-G Histocompatibility Antigen; Class I; G; MHC Class I Antigen G; B2 Microglobulin; HLA G Antigen; HLA Class I Histocompatibility Antigen; Alpha Chain G; Mutant MHC Class Ib Antigen; Mutant MHC Class I Antigen; MHC Class Ib Antigen; HLA-6.0; MHC-G; H
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered clear solution.HLA-G (Major Histocompatibility Complex Class I G) is a member of the HLA class I heavy chain paralogues. This class I molecule is a heterodimer which comprises a heavy chain as well as a light chain; beta-2 microglobulin; while the heavy chain is fixed in the membrane. HLA-G is expressed on fetal derived placental cells. HLA-G is a non-classical class-I HLA molecule linked with immuno-modulatory & anti-inflammatory properties which interacts with inhibitory receptors such as; ILT2/ILT4/KIR2DL4; that are present on different immune cells. HLA-G inhibits the proliferation of T cells; B cells & natural killer cells; moreover it also induces regulatory T cells.HLA-G Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 309 amino acids (25-308 a.a) and having a molecular mass of 35.3kDa.HLA-G is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
