FGG Human
Product Sizes
2 µg
£452.00
32-13233-2UG
10 µg
£528.00
32-13233-10UG
About this Product
- SKU:
- 32-13233
- Additional Names:
- Fibrinogen gamma chain isoform gamma-A; Fibrinogen gamma chain; PRO2061.
- Extra Details:
- Source: Escherichia Coli.Sterile Filtered clear solution.Fibrinogen gamma chain isoform gamma-A (FGG) is the gamma component of fibrinogen; which is a blood-borne glycoprotein; comprised of 3 pairs of nonidentical polypeptide chains. FGG along with fibrinogen alpha (FGA) and fibrinogen beta (FGB) polymerizes to form an insoluble fibrin matrix. Following vascular injury; FGG is cleaved by thrombin to create fibrin; which is the most abundant component of blood clots. FGG functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Moreover; different cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading; exhibit vasoconstrictor and chemotactic activities; and are mitogens for a number of cell types. Maternal fibrinogen is vital for successful pregnancy. FGG gene mutations lead to some disorders; including dysfibrinogenemia; hypofibrinogenemia and thrombophilia. Fibrin accumulation is also linked with infection; where it protects against IFNG-mediated hemorrhage.FGG Human Recombinant produced in E.Coli is a single; non-glycosylated polypeptide chain containing 434 amino acids (27-437 a.a) and having a molecular mass of 48.9kDa.FGG is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
- Purification:
- Greater than 90.0% as determined by SDS-PAGE.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C if entire vial will be used within 2-4 weeks. Store; frozen at -20[o]C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
