F8 Human
Product Sizes
200 IU
£913.00
32-13223-200IU
400IU
£1332.00
32-13223-400IU
About this Product
- SKU:
- 32-13223
- Additional Names:
- Coagulation factor VIII; Procoagulant component; Antihemophilic factor; AHF; F8; F8C; F8B; HEMA; FVIII; DXS1253E; F8 protein.
- Extra Details:
- Source: Human Plasma. Sterile Filtered White lyophilized (freeze-dried) powder. Coagulation factor VIII participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which; in the presence of Ca+2 and phospholipids; converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein; isoform a; which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein; isoform b; which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A; a common recessive X-linked coagulation disorder. Human Factor VIII produced from Human Plasma contains 2332 amino acids and having a molecular mass of 330kDa. Factor-VIII is effective in the correction and prevention of severe bleeding episodes attributed to Factor VIII deficiency. The Factor-VIII is purified by proprietary chromatographic techniques.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Lyophilized Factor-VIII although stable at room temperature for 1 week; should be stored desiccated between 2-8[o]C. Upon reconstitution Factor-VIII should be stored at 4[o]C.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
